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Protein aggregation in association with delayed neuronal death in rat model of brain ischemia
GE Pengfei, FU Shuanglin, LI Wenchen, WANG Chonghao, ZHOU Chuibing, LUO Yinan, LUO Tianfei
《医学前沿(英文)》 2008年 第2卷 第1期 页码 70-74 doi: 10.1007/s11684-008-0013-2
Shuai Ma, Huan Zhang, Xiaoyan Dong, Linling Yu, Jie Zheng, Yan Sun
《化学科学与工程前沿(英文)》 2018年 第12卷 第2期 页码 283-295 doi: 10.1007/s11705-017-1687-2
关键词: Alzheimer’s disease amyloid β-protein cyclic peptide inhibition protein aggregation
《化学科学与工程前沿(英文)》 2023年 第17卷 第12期 页码 2061-2073 doi: 10.1007/s11705-023-2366-0
关键词: organogelator tetraphenylvinyldrazone single crystal aggregation-induced emission effect ion sensing
Effects of humic acid and surfactants on the aggregation kinetics of manganese dioxide colloids
Xiaoliu HUANGFU,Yaan WANG,Yongze LIU,Xixin LU,Xiang ZHANG,Haijun CHENG,Jin JIANG,Jun MA
《环境科学与工程前沿(英文)》 2015年 第9卷 第1期 页码 105-111 doi: 10.1007/s11783-014-0726-1
关键词: humic acid surfactant aggregation kinetics drinking water manganese dioxide colloids
Influence of extracellular polymeric substances from activated sludge on the aggregation kinetics of
《环境科学与工程前沿(英文)》 2022年 第16卷 第2期 doi: 10.1007/s11783-021-1450-2
• The NPs aggregation in the electrolyte solution is consistent with the DLVO theory.
关键词: Silver nanoparticles Silver sulfide nanoparticles Extracellular polymeric substances Aggregation kinetics Influence mechanisms
Xi-hua Li,Xiao-hong Chen
《工程管理前沿(英文)》 2015年 第2卷 第3期 页码 266-276 doi: 10.15302/J-FEM-2015048
关键词: multi-criteria decision making trapezoidal intuitionistic fuzzy numbers Choquet integral fuzzy measure aggregation operator
Controlling interstory drift ratio profiles via topology optimization strategies
《结构与土木工程前沿(英文)》 2023年 第17卷 第2期 页码 165-178 doi: 10.1007/s11709-022-0892-3
关键词: interstory drift ratio aggregation function bound formulation min–max problem topology optimization
Systems understanding of plant–pathogen interactions through genome-wide protein–protein interaction
Hong LI,Ziding ZHANG
《农业科学与工程前沿(英文)》 2016年 第3卷 第2期 页码 102-112 doi: 10.15302/J-FASE-2016100
关键词: plant–pathogen interactions systems biology omics plant immunity protein–protein interaction network
Teza Mwamulima, Xiaolin Zhang, Yongmei Wang, Shaoxian Song, Changsheng Peng
《环境科学与工程前沿(英文)》 2018年 第12卷 第2期 doi: 10.1007/s11783-017-0979-6
关键词: Zero valent iron Bentonite Fly ash Heavy metals removal Synthesis
The role of protein kinase C epsilon in neural signal transduction and neurogenic diseases
null
《医学前沿(英文)》 2011年 第5卷 第1期 页码 70-76 doi: 10.1007/s11684-011-0119-9
Protein kinase C epsilon (PKC ?) is one of major isoforms in novel PKC family. Although it has been extensively characterized in the past decade, the role of PKC ? in neuron is still not well understood. Advances in molecular biology have now removed significant barriers to the direct investigation of PKC ? functions in vivo, and PKC ? has been increasingly implicated in the neural biological functions and associated neurogenic diseases. Recent studies have provided important insights into the influence of PKC ? on cortical processing at both the single cell level and network level. These studies provide compelling evidence that PKC ? could regulate distinct aspects of neural signal transduction and suggest that the coordinated actions of a number of molecular signals contribute to the specification and differentiation of PKC ? signal pathway in the developing brain.
关键词: protein kinase C ? signal transduction neurogenic disease
Autogenous healing mechanism of cement-based materials
《结构与土木工程前沿(英文)》 页码 948-963 doi: 10.1007/s11709-023-0960-3
关键词: autogenous healing cement-based materials healing mechanism aggregation effect
Wheat gluten protein and its impacts on wheat processing quality
Wujun MA, Zitong YU, Maoyun SHE, Yun ZHAO, Shahidul ISLAM
《农业科学与工程前沿(英文)》 2019年 第6卷 第3期 页码 279-287 doi: 10.15302/J-FASE-2019267
Before the advent of the wheat genomic era, a wide range of studies were conducted to understand the chemistry and functions of the wheat storage proteins, which are the major determinants of wheat flour the suitability of wheat flour for various end products, such as bread, noodles and cakes. Wheat grain protein is divided into gluten and non-gluten fractions and the wheat processing quality mainly depends on the gluten fractions. Gluten provides the unique extensibility and elasticity of dough that are essential for various wheat end products. Disulfide bonds are formed between cysteine residues, which is the chemical bases for the physical properties of dough. Based on the SDS-extractability, grain protein is divided into SDS-unextractable polymeric protein (UPP) and SDS-extractable polymeric protein. The percentage of UPP is positively related to the formation of disulfide bonds in the dough matrix. In the wheat genomic era, new glutenins with long repetitive central domains that contain a high number of consensus hexapeptide and nonapeptide motifs as well as high content of cysteine and glutamine residues should be targeted.
关键词: wheat gluten consensus motifs disulfide bonds SDS-unextractable polymeric protein glutenins gliadins processing quality storage protein
《化学科学与工程前沿(英文)》 2023年 第17卷 第8期 页码 1131-1139 doi: 10.1007/s11705-023-2321-0
关键词: biomass riboflavin sodium phosphate silk protein multifunctional modification flame retardant
Antithrombin deficiency and decreased protein C activity in a young man with venous thromboembolism:
null
《医学前沿(英文)》 2018年 第12卷 第3期 页码 319-323 doi: 10.1007/s11684-017-0553-4
Antithrombin and protein C are two crucial members in the anticoagulant system and play important roles in hemostasis. Mutations in and lead to deficiency or dysfunction of the two proteins, which could result in venous thromboembolism (VTE). Here, we report a Chinese 22-year-old young man who developed recurrent and serious VTE in cerebral veins, visceral veins, and deep veins of the lower extremity. Laboratory tests and direct sequencing of and were conducted for the patient and his family members. Coagulation tests revealed that the patient presented type I antithrombin deficiency combined with decreased protein C activity resulting from a small insertion mutation c.848_849insGATGT in and a short deletion variant c.572_574delAGA in . This combination of the two mutations was absent in 400 healthy subjects each from southern and northern China. Then, we summarized all the mutations of the and gene reported in the Chinese Han population. This study demonstrates that the combination of antithrombin deficiency and decreased protein C activity can result in severe VTE and that the coexistence of different genetic factors may increase the risk of VTE.
关键词: antithrombin deficiency protein C activity mutation variant venous thromboembolism anticoagulants
Baicheng HUANG, Kegong TIAN
《农业科学与工程前沿(英文)》 2020年 第7卷 第2期 页码 218-226 doi: 10.15302/J-FASE-2020324
Emergent coronaviruses (CoVs) such as SARS-CoV and MERS-CoV have posed great threats to public health worldwide over the past two decades. Currently, the emergence of SARS-CoV-2 as a pandemic causes greater public health concern. CoV diversity is due to the large size and replication mechanisms of the genomes together with having bats as their optimum natural hosts. The ecological behavior and unique immune characteristics of bats are optimal for the homologous recombination of CoVs. The relationship of spatial structural characteristics of the spike protein, a protein that is critical for recognition by host receptors, in different CoVs may provide evidence in explaining the coevolution of CoVs and their hosts. This information may help to enhance our understanding of CoV evolution and thus provide part of the basis of preparations for any future outbreaks.
关键词: bat coronavirus evolution host receptor spike protein transmission
标题 作者 时间 类型 操作
Protein aggregation in association with delayed neuronal death in rat model of brain ischemia
GE Pengfei, FU Shuanglin, LI Wenchen, WANG Chonghao, ZHOU Chuibing, LUO Yinan, LUO Tianfei
期刊论文
Head-to-tail cyclization of a heptapeptide eliminates its cytotoxicity and significantly increases its inhibition effect on amyloid
Shuai Ma, Huan Zhang, Xiaoyan Dong, Linling Yu, Jie Zheng, Yan Sun
期刊论文
Synthesis and ultraviolet/aggregation-induced emission investigation of novel tetraphenylvinyl hydrazone
期刊论文
Effects of humic acid and surfactants on the aggregation kinetics of manganese dioxide colloids
Xiaoliu HUANGFU,Yaan WANG,Yongze LIU,Xixin LU,Xiang ZHANG,Haijun CHENG,Jin JIANG,Jun MA
期刊论文
Influence of extracellular polymeric substances from activated sludge on the aggregation kinetics of
期刊论文
Trapezoidal Intuitionistic Fuzzy Aggregation Operator Based on Choquet Integral and Its Application to
Xi-hua Li,Xiao-hong Chen
期刊论文
Systems understanding of plant–pathogen interactions through genome-wide protein–protein interaction
Hong LI,Ziding ZHANG
期刊论文
Novel approach to control adsorbent aggregation: iron fixed bentonite-fly ash for Lead (Pb) and Cadmium
Teza Mwamulima, Xiaolin Zhang, Yongmei Wang, Shaoxian Song, Changsheng Peng
期刊论文
The role of protein kinase C epsilon in neural signal transduction and neurogenic diseases
null
期刊论文
Wheat gluten protein and its impacts on wheat processing quality
Wujun MA, Zitong YU, Maoyun SHE, Yun ZHAO, Shahidul ISLAM
期刊论文
Construction of sustainable, colored and multifunctional protein silk fabric using biomass riboflavin
期刊论文
Antithrombin deficiency and decreased protein C activity in a young man with venous thromboembolism:
null
期刊论文